Detalhe da pesquisa
1.
Identification of environmental factors that promote intestinal inflammation.
Nature
; 611(7937): 801-809, 2022 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-36266581
2.
Optimization of a series of heterocycles as survival motor neuron gene transcription enhancers.
Bioorg Med Chem Lett
; 27(23): 5144-5148, 2017 12 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-29103974
3.
Lipase regulation of cellular fatty acid homeostasis as a Parkinson's disease therapeutic strategy.
NPJ Parkinsons Dis
; 8(1): 74, 2022 Jun 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-35680956
4.
Short-duration splice promoting compound enables a tunable mouse model of spinal muscular atrophy.
Life Sci Alliance
; 4(1)2021 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-33234679
5.
Nanotherapeutic approaches to overcome distinct drug resistance barriers in models of breast cancer.
Nanophotonics
; 10(12): 3063-3073, 2021 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-34589378
6.
Barcoded viral tracing of single-cell interactions in central nervous system inflammation.
Science
; 372(6540)2021 04 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-33888612
7.
Pyrido[2,3-b]pyrazines, discovery of TRPV1 antagonists with reduced potential for the formation of reactive metabolites.
Bioorg Med Chem Lett
; 20(15): 4359-63, 2010 Aug 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-20615696
8.
Restoring tripartite glutamatergic synapses: A potential therapy for mood and cognitive deficits in Gulf War illness.
Neurobiol Stress
; 13: 100240, 2020 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-33344696
9.
Enhancement of tripartite synapses as a potential therapeutic strategy for Alzheimer's disease: a preclinical study in rTg4510 mice.
Alzheimers Res Ther
; 11(1): 75, 2019 08 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-31439023
10.
2-Arylpyrimidines: novel CRF-1 receptor antagonists.
Bioorg Med Chem Lett
; 18(16): 4486-90, 2008 Aug 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-18672365
11.
The design, synthesis and structure-activity relationships of 1-aryl-4-aminoalkylisoquinolines: a novel series of CRF-1 receptor antagonists.
Bioorg Med Chem Lett
; 18(3): 891-6, 2008 Feb 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-18180159
12.
1-Benzylbenzimidazoles: the discovery of a novel series of bradykinin B(1) receptor antagonists.
Bioorg Med Chem Lett
; 18(18): 5027-31, 2008 Sep 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-18752949
13.
Aminoquinazolines as TRPV1 antagonists: modulation of drug-like properties through the exploration of 2-position substitution.
Bioorg Med Chem Lett
; 18(16): 4573-7, 2008 Aug 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-18662872
14.
Pyridazine-derivatives Enhance Structural and Functional Plasticity of Tripartite Synapse Via Activation of Local Translation in Astrocytic Processes.
Neuroscience
; 388: 224-238, 2018 09 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-30056115
15.
Discovery of a Small Molecule Probe That Post-Translationally Stabilizes the Survival Motor Neuron Protein for the Treatment of Spinal Muscular Atrophy.
J Med Chem
; 60(11): 4594-4610, 2017 06 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-28481536
16.
Small Molecules in Development for the Treatment of Spinal Muscular Atrophy.
J Med Chem
; 59(22): 10067-10083, 2016 11 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-27490705
17.
Restored glial glutamate transporter EAAT2 function as a potential therapeutic approach for Alzheimer's disease.
J Exp Med
; 212(3): 319-32, 2015 Mar 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-25711212
18.
Synthesis of 2-aryl-oxazolo[4,5-c]quinoline-4(5H)-ones and 2-aryl-thiazolo[4,5-c]quinoline-4(5H)-ones.
Org Lett
; 5(16): 2911-4, 2003 Aug 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-12889906
19.
Regiocontrolled synthesis of substituted thiazoles.
Org Lett
; 4(8): 1363-5, 2002 Apr 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-11950363
20.
Ethyl 2-chlorooxazole-4-carboxylate: a versatile intermediate for the synthesis of substituted oxazoles.
Org Lett
; 4(17): 2905-7, 2002 Aug 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-12182585